Respiratory Insufficiency
Conditions
Brief summary
Postoperative pulmonal complications (Abbreviation - PPC) after major abdominal surgery remains a significant clinical problem delaying rehabilitation after surgery. CPAP is one approach to minimize the frequency and severeness of PPC. In the investigators' organization intermittent mask CPAP every 2 hour, 15min, is used routineously after major abdominal surgery. Recently new devices has been designed, which give the opportunity tip deliver continuously CPAP with out interruptions because of presumed better comfort. Therefore better patient compliance. No studies to date have investigated the possible benefit of using continuously helm CPAP versus the traditional intermittent mask CPAP after major abdominal surgery. The investigators' study will investigate if there are any benefits with continuously Helm CPAP Versus intermittent Mask CPAP After Major Abdominal Surgery.
Interventions
DEVICEContinuously helm CPAP
6 hours
DEVICEIntermittent Mask CPAP
10min every 2 hour for 18 hours
Sponsors
Rigshospitalet, Denmark
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Elective major abdominal surgery
Exclusion criteria
* Severe lung disease. Airway deformity. Need for CPAP at home. Ongoing oxygen therapy. Cannot give informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| PaO2/FiO2 | 24 hours | Measured 6,12 and 18 hours after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative complications | 30 days | Pulmonal complications defined as; needs of oxygen therapy more than 3 days after surgery, pneumonia and x-ray verified atelektases within 30 days after surgery. |
| Length of stay | 30 days | Length of stay |
| Admittance to the intensive care unit | 30 days | If needed. Cause and length of stay in the intensive care unit i recorded. |
| Mortality | 30 days | Mortality |
| V/Q mismatch | 24 hours | V/Q mismatch measured with ALPE essential®. Meassured preoperative, on arrival in the postoperative ward and 24 hours postoperative. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Comfort during CPAP therapy | 24 timer | The comfort during CPAP therapy. Measured on an numeric rang scale from 0-10, where 0 is no discomfort and 10 is extensive discomfort during CPAP. |
| CPAP interruptions | 24 timer | Length and cause of the interruptions are noted |
| Total CPAP therapy time | 24 timer | Measured in total minutes |
Countries
Denmark
Contacts
Primary ContactKlaus V Marcussen, MD
Backup ContactLara SP Henningsen, Nurse
Outcome results
None listed