Atrial Fibrillation
Conditions
Keywords
Atrial fibrillation, Virtual ablation, electrocardiography, electroanatomical mapping data
Brief summary
Radiofrequency catheter ablation is highly effective in the treatment of patients with persistent atrial fibrillation. In order to decrease the recurrence rate after catheter ablation, the investigators propose to apply 'virtual' ablation on patient-specific atria by simulating 3D atrial computer model. The investigators will test with five different set of ablation methods and find successful methods for a specific patient. Then, this result will be compared to empirical catheter ablation result by randomly controlled trial.
Interventions
PROCEDUREVirtual ablation in based 3D CT of patient who diagnosed AF
PROCEDUREconventional ablation based on physician's personal experience
Sponsors
Yonsei University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis of AF patients who performed catheter ablation of atrial fibrillation due to uncontrolled pulse rate by anti-arrhythmic drug therapy.
Exclusion criteria
* AF patients who have severe heart deformations or blood problems. * The patients who had been performed catheter ablation of atrial ablation. * The patients who missed out to recording of 3D CT, echo and electrocardiography.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of hospitalization rate | 1, 3, 6, 12, 18 and 24 months after catheter ablation and every 6 months thereafter. |
Secondary
| Measure | Time frame |
|---|---|
| occurence of cardiovascular disease | 6 months |
| recurrence of AF | 6 months |
Countries
South Korea
Outcome results
None listed