Oropharyngeal Dysphagia
Conditions
Keywords
neuromodulation, swallowing, magnetic stimulation, healthy subjects
Brief summary
The aim of this study is to test the hypothesis that rTMS on the dominant swallowing hemisphere is able to modify swallowing coordination.
Detailed description
The aim of the study is to demonstrate that rTMS (on the dominant hemisphere, on the nondominant hemisphere and placebo rTMS) are able to modify swallowing coordination on healthy subjects. Swallowing function will be studied before and after rTMS with videomanometry.
Interventions
PROCEDUREmagnetic stimulation
rTMS on pharyngeal cortical area in healthy subjects or sham rTMS on pharyngeal cortical area in healthy subjects
Sponsors
University Hospital, Rouen
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* 18-50 years old * healthy subjects
Exclusion criteria
* epilepsia * brain injury * stroke * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| pharyngeal pressure | Day 1 | Swallowing function will be studied before and after rTMS with videomanometry |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| swallowing time | Day 1 | Swallowing function will be studied before and after rTMS with videomanometry |
Countries
France
Outcome results
None listed