Atrial Fibrillation
Conditions
Brief summary
Atrial Fibrillation is an abnormal heart rhythm that can occur after coronary heart bypass graft operations. How often this happens and what other problems occur for a person after these operations needs to be better understood. This study uses a device called the Reveal XT, a small device that records heart rhythms to track a patient's heart rhythms after the bypass surgery. The device is implanted at the time the bypass graft is made. The information that is gathered for this study will help physicians to provide better treatment and follow-up of the patients under their care.
Detailed description
We will utilize the Reveal XT implantable loop recorder (ILR) in order to monitor the incidence of AF in our post-CABG patients. The Reveal XT has been shown to be superior in comparison to the more commonly used sporadic ECGs.6 Unfortunately, the occurrences of arrhythmias tend to be unpredictable and often paroxysmal. Observers are unlikely to have the opportunity to record ECGs at the time of event until it is too late. The ability of the Reveal XT to continuously record ECGs over long periods of time has made it a superior and powerful diagnostic tool in patients with arrhythmias and arrhythmia related complications. This was evident in the large multicenter PICTURE study whereby a large number of diagnostic tests were undertaken in patients with unexplained syncope without providing conclusive data, but in the same study with the Reveal ILR, the mechanism of syncope in the vast majority of these patients were established often at first onset of an arrhythmia.7 The equivalent efficacy, if not superiority, of Reveal ILRs above conventional ECGs and Holter-monitors in detecting AF was established in the XPECT trial.8 Its sensitivity in detecting events not seen with ECGs and Holter monitoring post COX MAZE procedure (surgical procedure for AF) and post ablations for paroxysmal AF and persistent AF is well established.
Interventions
None listed
Sponsors
Saint Thomas Health
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 60 years of age or older * Presenting for elective Coronary Artery Bypass Graft at Saint Thomas West Hospital
Exclusion criteria
* Patients \<60 years of age * Prior cardiac surgery * Emergent surgery * Need for concomitant cardiac surgery other than PFO closure * Prior history of AF or Atrial flutter * Prior atrial ablation * Prior cardioversion * Patients with prior permanent pacemaker * Ejection fraction \<35% * Prior history of thyroid disease * Prior history of a cardiomyopathy * Patients without telephonic access
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number and cost of atrial fibrillation after coronary artery bypass grafting (CABG) per patient | Three year follow-up | Patient follow up |
| Number of complication s related to atrial fibrillation in patients after CABG | 3 year follow up | Patient follow up |
| Number of therapeutic/intervention changes for participants post CABG resulting from use | 3 year follow up | Patient follow up |
Countries
United States
Outcome results
None listed