Fecal Incontinence
Conditions
Brief summary
Background: Biofeedback and medical treatments have been extensively used for moderate fecal incontinence. There is limited data comparing and combining these two treatments. Aim: To evaluate the effect of biofeedback and medical treatments, separately and in combination. Methods: Sixty-five consecutive female patients, referred to a tertial center for fecal incontinence were included. The patients were randomized to start with either biofeedback (4-6 months) or medical treatment with loperamide and stool-bulking agents (2 months). Both groups continued with a combination treatments, i.e. medical treatment was added to biofeedback and vice versa. A two-week prospective bowel symptom diary and anorectal physiology were evaluated at baseline, after single- and combination treatments.
Interventions
BEHAVIORALBiofeedback
DRUGLoperamide
DRUGStool bulking agent (stericulia or isphagula husk)
OTHERCombination of biofeedback and medical treatment
Sponsors
University Hospital, Linkoeping
Study design
Primary purpose
TREATMENT
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients older than 18 years of age * Patients with at least one or more episodes of FI during a period of 2 weeks as recorded by bowel function diary * Patients from whom written consent was obtained
Exclusion criteria
* Previous congenital or acquired spinal injury, spinal tumour or spinal surgery * Presence of neurological diseases or peripheral vascular disease * Uncontrolled diabetes mellitus * Congenital anorectal malformations * Recent colorectal or gastrointestinal surgery * Presence of external full-thickness rectal prolapse * Inflammatory bowel disease * Chronic diarrhoea * Use of tibial nerve or sacral nerve stimulations * Ongoing pregnancy * Any malignant disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| symptom diary | Up to eight months |
Countries
Sweden
Outcome results
None listed