Skip to content

Total Knee Arthroplasty Analgesia: Single-shot Femoral Nerve Block or Epidural?

Comparison Between Single-shot Femoral Nerve Block and Epidural Techniques for Total Knee Arthroplasty: a Randomized Controlled Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02164825
Enrollment
60
Registered
2014-06-17
Start date
2014-01-31
Completion date
2014-08-31
Last updated
2015-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain Treatment for Total Knee Arthroplasty

Brief summary

Single-shot femoral nerve block is similar to continuous epidural technique for postoperative analgesia in total knee arthroplasty

Interventions

DRUGRopivacaine perineural injection

Ultrasound guided single-shot femoral nerve block

DRUGmorphine and ropivacaine

Continuous epidural analgesic perfusion Epidural perfusion with morphine and ropivacaine.

Sponsors

Centro Hospitalar do Tâmega e Sousa
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Elective total knee arthroplasty

Exclusion criteria

* Coagulopathy * Neuropathy * Morbid obesity * local anesthetics allergy

Design outcomes

Primary

MeasureTime frameDescription
Pain Score on the numeric pain score48 hoursPatients will be evaluated at 48 hours. At these time frame pain score at rest and during movement will be accessed.

Secondary

MeasureTime frameDescription
Side effects as a measure of safety and tolerability48 hoursSide effects of both interventions. Number of patients with side effects like nausea, vomiting, hypotension and pruritus.
Rescue analgesic consumption.48 hoursOpioid rescue needs in the first 48 hours after surgery.
Patients satisfaction.48 hoursEvaluation of patient´s satisfaction with pain control (asking the patient to classify the grade of satisfaction).

Countries

Portugal

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026