Agitation, Pediatric Disorder
Conditions
Keywords
sevoflurane, pediatric, lower abdominal surgery, caudal, magnesium sulfate, Magnesium Sulfate Causing Adverse Effects in Therapeutic Use, Agitation States as Acute Reaction to Exceptional Stress
Brief summary
Emergence agitation after sevoflurane anesthesia is still a problem needed to be solved.The aim of the study is to delineate the effect of caudal magnesium sulfate in children undergoing lower abdominal surgery to prevent postoperative emergence agitation.
Detailed description
Emergency agitation is considered one of the postoperative complication after sevoflurane anesthesia.In the enrollment of this study,children undergoing lower abdominal surgery will be enrolled in one of two groups.BM group, receive caudal magnesium sulfate 50 mg beside the conventional bupivacaine in the caudal space in ,B group, addition of 1 ml of normal saline0.9% to bupivacine .Monitoring of the postoperative emergence agitation by different emergence agitation scores with monitoring of sedation score.Detection of expected postoperative complications as nausea and vomiting.
Interventions
DRUGMagnesium Sulfate
use of 50mg magnesium sulfate in caudal analgesia added to 1ml/kg of 0.25% of bupivacaine in children undergoing lower abdominal surgery for prevention of postoperative emergence agitation.
DRUG0.9%normal saline
use of 1ml of 0.9%normal saline added to 1ml/kg of 0.25% of bupivacaine in the caudal block as placebo to compare with active comparator.
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
MALE
Age
1 Years to 6 Years
Healthy volunteers
No
Inclusion criteria
* children undergoing lower abdominal surgery for hernia repair/orchiopexy in Ain Shams University ASA physical status I under sevoflurane anesthesia. * age from 1-6 years.
Exclusion criteria
* children with developmental delay * neurological disorder. * psychological disorder * difficult airway * hyperactive airway disease * contraindication to caudal block(sacral abnormality,bleeding disorder).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measure of postoperative pediatric anesthesia emergence delirium PAED score | first 30 minutes postoperative | measurement of PAED score every 5 minutes in the first 30 minutes after lower abdominal surgery in children 1-6 year age after sevoflurane anesthesia. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| measure of postoperative sedation score. | the first 30 minutes postoperatively | use of sedation score as a measure of postoperative sedation expected after caudal magnesium sulfate every 5 minutes for 30 minutes after end of surgery. |
Other
| Measure | Time frame | Description |
|---|---|---|
| postoperative rescue propofol intravenous 1mg/kg in cases if agitation | first 30 minutes postoperative | if emergence agitation occur giving of 1mg/kg of intravenous propofol as rescue medication |
Countries
Egypt
Contacts
Primary Contactashraf elsayed elagamy, MD anesthesia
Backup Contactwael yahir
Outcome results
None listed