The Use of Tranexamic Acid (TXA) Intravenously, to Reduce Blood Loss in Proximal Femur Surgery

Status

Withdrawn

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02164565

Enrollment

Registered

2014-06-16

Start date

2014-06-30

Completion date

2015-03-31

Last updated

2017-08-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Femur Surgery

Brief summary

The use of Tranexamic Acid (TXA) intravenously, to Reduce Blood Loss in proximal femur surgery.

Interventions

DRUGTranexamic Acid (TXA) treatment

Tranexamic Acid (TXA) treatment

DRUGcontrol grup: without Tranexamic Acid (TXA) treatment.

control grup: without Tranexamic Acid (TXA) treatment.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

60 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients over 60, who came to the orthopedic department for proximal femur fracture surgery * Sound judgment

Exclusion criteria

* Known hypersensitivity to Tranexamic Acid or component solution provided * Subarachnoid hemorrhage * Acquired color blindness * Myocardial infarction in 12 months before admission * Unstable angina * Known clotting disorders (Thromboembolic disease in the past, elongated PT and PTT, hypercoagulability), * Kidney or liver failure * Another situation prostate resection , pathologic fractures according to anamnesis or by imaging * Oncology patients * Patients on anticoagulation * Patients undergoing vascular intervention ( coronary or peripheral ), which was inserted Supporter requires a Dual antiplatelet therapy

Design outcomes

Primary

Measure	Time frame	Description
Evaluation of blood loss in ml.	up to 13 months	Hbloss=BV X (Hbi - Hbe) X 0.001 + Hbt Hbi - hemoglobin level before the surgery ) gram X liter-1(. Hbe - hemoglobin level 3 days after the surgery ( gram X liter-1). Hbt - The amount of hemoglobin that was given in the blood transfusion (gram). Hbloss - Change of hemoglobin loss. After calculating the amount of loss of hemoglobin, the volume of blood lost can be found: Blood loss = 1000 X Hbloss/ Hbi Evaluation of blood loss will be through: 1\. Comparing hemoglobin level before and after surgery and calculation of quantitative Change of hemoglobin loss. 2 .Registration evaluating blood loss at the end of surgery 3. Collecting and recording blood drain. 4. Tracking Blood Transfusion. Of course we collect the data: assessment of bleeding in the analysis, the number of blood units given, the amount of blood collected drain

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026