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Effects of Yoga on Bone Metabolism in Premenopausal Women

Effects of an 8-month Yoga Intervention on Bone Metabolism in Healthy Middle-aged Premenopausal Women: A Randomized Controlled Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02163668
Enrollment
47
Registered
2014-06-16
Start date
2009-09-30
Completion date
2012-04-30
Last updated
2014-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Health, Osteoporosis

Keywords

Yoga, Bone turnover markers, Bone strength, Bone mineral density

Brief summary

This study examined the effects of 8 months of Yoga training on bone density and bone turnover markers in premenopausal women, ages 35-50 years. The style of Yoga used was power Yoga that involved postures with a jumping component. The investigators hypothesized that the Yoga intervention would result in beneficial improvements in bone turnover markers, by increasing the bone formation marker and decreasing the bone resorption marker.

Interventions

8 months of Yoga training

Sponsors

University of Oklahoma
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
35 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* participants had not been engaged in resistance training or in Yoga exercise for at least 12 months prior to the study * did not have chronic back or joint problems or cardiovascular disease * not taking antihypertensive drugs or any medication that affects bone density * not taking hormonal contraception * they self-reported having regular menstrual cycles.

Exclusion criteria

* body weight more than 300 pounds

Design outcomes

Primary

MeasureTime frameDescription
Change in Insulin-like Growth Factor-1 (IGF-I) and Insulin-like Growth Factor BP3 (IGFBP3)pre and post 8 month intervention
Change in bone mineral density from baseline to 8 monthspre and post 8 months training
change in bone turnover markerspre and post 8 month intervention
change in tibia bone characteristicspre and post 8 month interventionchanges in volumetric bone mineral density and bone strength of the non-dominant tibia assessed by peripheral Quantitative Computed Tomography (pQCT)
Changes in muscular strengthpre and post 9 month interventionIsotonic 1 repetition maximum (1RM) for 4 lower body and 2 upper body resistance exercises
Change in arterial compliancepre and post 8 month interventonArterial compliance of the large and small arteries was assessed using Pulse Contour analysis.

Secondary

MeasureTime frameDescription
Menstrual Historypre and post 8 month interventionThis information was used to monitor menstrual characteristics to ensure they were still premenopausal at the post test.
Dietary intakeAt baseline at the same time as other outcomes, about 2 weeks before the beginning of the yoga trainingThree day dietary logs were recorded by participants before the exercise intervention. They were analyzed for caloric intake and nutrient composition using the Diet Analysis Plus 9 software.
Change in physical activity levelspre and post 8 month interventionPhysical activity levels estimated by the bone-specific physical activity (PA) questionnaire to monitor their PA outside of the intervention
Change in body compositionpre and post 8 month intervention
Daily Calcium intakepre and post 8 month interventionCalcium intake is a potential confounding variable. Participants were encouraged to increase their calcium intakes if found to be low before the intervention began.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026