Mild Traumatic Brain Injury
Conditions
Keywords
Mild traumatic brain injury, Cognitive outcome, Psychological outcome
Brief summary
Patients with traumatic brain injury are likely to present with cognitive, psychological, emotional and behavioral problems during different periods, all of which affect patients' life quality seriously. The aim of this study was to assess cognitive and psychosocial outcome in patients with mild traumatic brain injury, and to determine the risk factors associated with cognitive and psychological outcome. Mini-mental state examination (MMSE), activities of daily living scale (ADL), the Hospital Anxiety Depression Scale (HADS) and mental health symptom checklist (SCL-90) were used to assess the cognitive performance and psychological outcomes in 360 patients with mild traumatic brain injury. Chi-square, Fisher's exact tests and Logistic regression analysis were used to analyze the risk factors.
Interventions
None listed
Sponsors
Shanghai 6th People's Hospital
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* 18 \ 60 years old * Education: primary school and above, who could understand the content of psychological test * History of brain trauma * No taking of antipsychotic or any other drugs affecting central nervous system before the test * Glasgow coma score (GCS) was 13-15
Exclusion criteria
* History of craniocerebral injury, brain disease, mental disease * With mental retardation * with other serious body diseases * History of drug and alcohol dependence * With color-blind or color weakness * Who had severe visual and auditory disorders after brain injury * Who failed or failed in completing the test effectively * With cognitive impairment caused by the damage of the unilateral frontal or bilateral lobes, or with language dysfunction caused by temporal lobe damage
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mini-Mental State Examination | 6 months | MMSE includes seven factors, namely: the time orientation factor (5 points), place orientation (5 points), immediate memory (3 points), short-term memory (3 points), calculation capabilities (5 points), verbal expression, naming and repetition (4 points), speech reading and understanding (4 points), graphic depiction (1 points). The scales for the description of cognitive function impairment were grouped into three levels of education: illiteracy (17 points), primary school (20 points) and middle school (24 points). The one with score below average was considered with cognitive function impairment. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Activity of daily living scale | 6 months | The scale is divided into two parts: physical self-care ability, instrumental activities of daily living. 1 point for each option means normal; If 2\ 4 points for one option, he or she probably had ability decline; If two or more parts ≥3 points or total score≥ 22 points (14 questions), he or she exhibited living ability decline clearly. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Hospital anxiety and depression Scale | 6 months | The scale includes 14 items and each has 0-3 points. The score of the former seven items \> 7, indicating depression symptom; the later seven items \> 7, indicating anxiety symptom. |
| Symptom Check-List 90 | 6 months | This scale has been widely used to patients with neurosis, adjustment disorder and other slight mental psychological disorder. According to the national norm results, if the total score \> 160, or the number of positive items \> 43, or one factor score \>2, we consider the positive screening. |
Countries
China
Outcome results
None listed