Functional Brain Imaging and Psychological Testing in Women With Chronic Pelvic Pain

Status

Withdrawn

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02160483

Enrollment

Registered

2014-06-10

Start date

2015-06-01

Completion date

2016-06-01

Last updated

2026-08-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis of Uterus, Pelvis Pain Chronic

Keywords

Chronic pelvic pain, Endometriosis

Brief summary

Functional magnetic resonance imaging in women with chronic pelvic pain using arterial spin labelling, functional connectivity, diffusion tensor imaging and magnetic resonance spectroscopy.

Detailed description

Multimodal magnetic resonance neuroimaging will be utilised. Arterial spin labelling is tightly coupled with cerebral metabolism and can be used as a marker of neural activity. Resting state magnetic resonance imaging which measures synchronous activity across the brain, allows detection of functional connectivity of intrinsic brain network. Diffusion tensor imaging detects the anisotropic water diffusion in axonal fibres can provide information on connectivity and fibre tracts. Magnetic resonance spectroscopy would enable the levels of neurotransmitter to be elucidated.

Interventions

OTHERFunctional magnetic resonance imaging

3 Tesla magnetic resonance imaging

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

21 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Chronic pelvic pain * Endometriosis

Exclusion criteria

* Contraindication to magnetic resonance imaging

Design outcomes

Primary

Measure	Time frame	Description
Number of participants with increase in insula anterior cingulate cortex signal on magnetic resonance imaging	1 hour	Magnetic resonance imaging using arterial spin labelling, functional connectivity, diffusion tensor imaging, magnetic resonance imaging

Secondary

Measure	Time frame	Description
Number of subjects in psychological testing with increased anxiety, depression and pain catastrophizing scores	1 hour	Anxiety, depression and pain catastrophizing scales used for psychological testing

Countries

Singapore

Contacts

PRINCIPAL_INVESTIGATORBan L Sng, FANZCA

KK Women's and Children's Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 7, 2026