Comparison of Postoperative Analgesic Efficacy of Intravenous Dexketoprofen Trometamol With Tenoxicam

Comparison of Postoperative Analgesic Efficacy of Intravenous Dexketoprofen Trometamol With Tenoxicam in Lumbar Disc Surgery

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02160236

Enrollment

Registered

2014-06-10

Start date

2014-11-30

Completion date

2015-02-28

Last updated

2014-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Keywords

dexketoprofen trometamol, tenoxicam, postoperative pain

Brief summary

In this study the investigators aimed to compare of postoperative analgesic effects of intravenous dexketoprofen trometamol and tenoxicam in lumbar disc surgery.

Detailed description

Lumbar disc surgery is associated with moderate to severe back and radicular pain postoperatively which has unfavorable effects on patients recovery and procedures outcome. Dexketoprofen has been reported to be one of the NSAİDs that can provide good results when compared with narcotics in many painful conditions and especially in the treatment of the moderate to severe postoperative pain that may develop after lumbal disc surgery. Tenoxicam is a thienothiazine derivative of the oxicam class of NSAİDs. There are some studies in which NSAİDs have been used to together with opioids for postoperative analgesia showing that they decrease opioid consumption and side effects

Interventions

DRUGdexketoprofen trometamol

before end of the surgery via intravenous administration 50 mg dexketoprofen trometamol in 0.9 % NaCl 100 cc

DRUGtenoxicam

before the end of the surgery via administration intravenous 20 mg tenoxicam in 0.9% NaCl in 100 cc

DRUGserum physiologic

before end of the surgery via administration intravenous 0.9 % NaCl 100 cc

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* ASA 1-2 * between 18-65 age * elective lumbar disc surgery

Exclusion criteria

* history of gastrointestinal bleeding * peptic ulcer disease * bleeding disorders * history of allergic reactions to NSAİDs * chronic pain syndrome

Design outcomes

Primary

Measure	Time frame	Description
analgesic consumption	postoperative 1 day	morphine consumption (patient control analgesia procedure) was recorded

Secondary

Measure	Time frame	Description
visual analog scale	postoperative 1 day	visual analog scale on rest and movement was recorded

Countries

Turkey (Türkiye)

Contacts

Primary ContactNazife Küçük, resident

nzfkucuk@hotmail.com+905072317446

Backup ContactHalit Madenoğlu, prof

halitm@erciyes.edu.tr+903522076666

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026