Chronic Periodontitis
Conditions
Brief summary
The investigators plan to recruit 40 healthy patients referred to the unit of Periodontology, diagnosed with generalized moderate - severe chronic periodontitis. treatment will include 4 - 6 sessions of scaling + root planning, oral hygiene instructions and motivation. Whole saliva will be collected at intake and 8 - 14 weeks post periodontal treatment. Saliva will be analyzed for trans locator protein. Study hypothesis: Periodontal treatment has an affect on saliva components.
Interventions
PROCEDUREperiodontal treatment - scaling and root planning
Sponsors
The Baruch Padeh Medical Center, Poriya
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* healthy patients * moderate - sever chronic periodontitis
Exclusion criteria
* systemic disease * pregnancy * subjects under the age of 18
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Whole saliva & translocator protein (TSPO) | Intake of patients than 8 - 12 weeks after periodontal treatment (scaling & root planning) | Change in whole saliva & translocator protein (TSPO) post periodontal treatment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Periodontal measurements (periodontal pocket depth, bleeding on probing & clinical attachment level) | Intake 8 - 12 weeks post periodontal treatment (scaling & root planning) | periodontal probing depth, bleeding on probing and clinical attachment level. |
Contacts
Primary ContactEran Front, DMD
Outcome results
None listed