Angina Pectoris
Conditions
Keywords
CABG, Saphenous vein, Radial artery
Brief summary
The investigators have developed a novel technique for saphenous vein graft harvesting for coronary artery bypass grafting (CABG) where the graft is harvested with a pedicle of surrounding tissue. A randomized trial has shown a significantly higher patency rate for vein grafts harvested with this new methode compared to conventional harvesting technique 8.5 years after surgery (90 vs 76 %). In 2004 the investigators started a prospective randomized trial comparing patency between vein grafts harvested with surrounding tissue and radial artery grafts. The result showed that vein grafts harvested with surrounding tissue had a significantly higher patency rate compared to radial artery grafts 3 years after surgery (98 vs 84 %). The present study is a long-term follow-up (8 years) of the patients included in the second randomized trial. The hypothesis is that vein grafts harvested with surrounding tissue have a significantly higher patency rate compared to radial artery grafts 8 years after surgery.
Interventions
PROCEDURENT SVG grafts
Sponsors
Region Örebro County
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
No minimum to 65 Years
Healthy volunteers
No
Inclusion criteria
* Three vessel coronary artery disease
Exclusion criteria
* 65 years or older * Elevated creatinine * Raynauds disease * Vein stripping
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Graft patency | 5 months | The grafts will be categorized as either open or closed. A stenosis of the graft exceeding 70 % of the lumen diameter will be considered as closed. |
Countries
Sweden
Outcome results
None listed