A Single High-dose Oral Supplement of Vitamin D in Young Chinese

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02158143

Enrollment

Registered

2014-06-06

Start date

2013-10-31

Completion date

Unknown

Last updated

2014-06-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin D Deficiency

Brief summary

evaluated the effect and safety of a single high dose of cholecalciferol in Chinese young people.

Interventions

DIETARY_SUPPLEMENTvitamin D3

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

25 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy, younger, Chinese Hans aged from 25-35 years, including 25 and 35 years; * haven't taken vitamin D supplement for the past 6 months; * with a normal BMI (18-25 kg/m2); * with baseline serum 25(OH)D \< 30 ng/ml; * be willing to follow the instruction and complete the study.

Exclusion criteria

* clinically diagnosed cardiovascular disease, gastrointestinal disease, endocrine, blood, liver, lung, kidney, nerve or mental illness; * self-reported current use of any dietary supplements containing vitamin D within the 6 months before enrollment; * Severe anemia (hemoglobin concentration \< 70 g/L); * Serum 25(OH)D ≥ 30 ng/mL at enrollment; * participating in other research studies within the 3 months before enrollment; * history of drug dependence or drug abuse; * History of heavy drinking (drinking 14 cups or more per week, equivalent to 360 mL beer or 150 mL white wine or 45 mL liquor per cup) and smokers (more than 10 cigarette per day); * clinical abnormal of blood biochemistry, hematology or urine laboratory values; * current pregnancy or lactation.

Design outcomes

Primary

Measure	Time frame
Effect of vitamin D3 supplementation on serum PTH	within 140 day after supplementation
Effect of vitamin D3 supplementation on serum creatinine	within 140 day of supplementation
Effect of vitamin D3 supplementation on urinary calcium / creatinine	within 140 day after supplementation
Effect of vitamin D3 supplementation on serum 25(OH)D changes	within 140 day after supplementation
Effect of vitamin D3 supplementation on serum calcium	within 140 day after supplementation

Secondary

Measure	Time frame
Effect of vitamin D3 supplementation on serum lipids	within 140 day after supplementation
Effect of vitamin D3 supplementation on fasting blood glucose	within 140 day after supplementation

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026