Effects of Aerobic Exercise Detraining

Effects of Aerobic Exercise Detraining on Energy Balance in Overweight Persons

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02158130

Acronym

E-Mechanic_Fol

Enrollment

Registered

2014-06-06

Start date

2014-09-30

Completion date

2016-03-31

Last updated

2016-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Body Weight, Motor Activity, Obesity

Keywords

Physical Inactivity, Aerobic Exercise Detraining, Body Weight, Energy Expenditure, Metabolic Syndrome

Brief summary

The proposed study seeks to better understand the role of body weight, energy expenditure, and energy intake as mechanisms of body weight gain during detraining following aerobic exercise. It is hypothesized that participants in the higher dose exercise group will have greater body weight gain compared to the lower exercise dose and control group from wk 24 to wk 76 follow-up.

Detailed description

Eligibility criteria include having successfully completed the main E-Mechanic study, be willing to archive blood samples and not being currently enrolled in another study that may effect body, energy intake or energy expenditure. The investigators will measure body weight, waist/hip circumference, blood pressure, body composition, physical activity, questionnaire about appetite/food intake and physical fitness.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 67 Years

Healthy volunteers

Yes

Inclusion criteria

* Completed the E-Mechanic study * Be willing to archive blood samples * Not participating in a study that would alter body weight, energy intake, or energy expenditure.

Design outcomes

Primary

Measure	Time frame	Description
Body Weight	Week 64 - 88 post study randomization	Fasting body weight

Secondary

Measure	Time frame	Description
Energy Expenditure	Week 64 - 90 since study randomization	Energy expenditure is calculated with the Sensewear Armband.
Energy Intake	Week 64 - 90 post study randomization	Energy expenditure is calculated with the Sensewear Armband and furthermore, energy intake is calculated by adjusting TDEE for change in body weight following the methods used in doubly labeled water adjustment.

Other

Measure	Time frame	Description
Triglycerides	Week 64 - 88 post study randomization	—
Circumferences	Week 64-88 post study randomization	Waist and hip circumferences
Cholesterol	Week 64 - 88 post study randomization	Total, HDL, and LDL cholesterol
Blood Pressure	Week 64-88 post study randomization	—
Body Composition	Week 64 - 88 post study randomization	Whole Body Scan GE iDXA (Dual energy x-ray absorptiometry)

Countries

United States

Outcome results