Endobronchial Ultrasound-transbronchial Needle Aspiration (EBUS-TBNA) Sample Division

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02157194

Enrollment

Registered

2014-06-05

Start date

2013-02-28

Completion date

2015-05-31

Last updated

2016-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Brief summary

EBUS-TBNA specimen are used for lung cancer diagnosing and staging, as well for molecular analysis. The purpose of this study is to evaluate if samples from on lymph node site can be divided for diagnosis and molecular analysis.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* clinical diagnosis of lung cancer * enlarged mediastinal or hilar lymph nodes (\>10 mm)

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Sensitivity and Specificity of lung cancer diagnosis	6 month	We aim to evaluate if splitting the obtained specimen will have an impact on lung cancer diagnosis performed by histopathologic analysis

Secondary

Measure	Time frame	Description
Percentage of successful performed molecular RNA based analysis	3 month	We will analyse the second half of the sample regarding molecular analysis. RNA concentration and RNA integrity score will be assessed before a new RNA based test will be evaluated.

Countries

Germany

Outcome results