Oxytocin and Emotion Processing

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02156661

Enrollment

Registered

2014-06-05

Start date

2013-05-31

Completion date

2014-06-30

Last updated

2017-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Males

Brief summary

The purpose of this study is to determine whether oxytocin influences emotional processing and learning of emotional and social stimuli.

Detailed description

An effect of OXT on emotion processing and anxiety has been broadly investigated in animal studies. However, in humans, effects seem more complex. The rationale of the study is to examine direct effects of OXT to processing and learning of emotional and social values in humans.

Interventions

DRUGOxytocin

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

MALE

Age

20 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy male volunteers

Exclusion criteria

* Current or past psychiatric disease * Current or past physical illness * Psychoactive medication * Tobacco smokers * MRI contraindication

Design outcomes

Primary

Measure	Time frame	Description
Brain activity	During emotion processing	fMRI

Secondary

Measure	Time frame	Description
Psychophysiological response	During stimuli presentation	Skin conductance response

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026