Thyroid Cancer
Conditions
Keywords
Thyroid carcinoma, predictive factors, refractory, Differentiated, follicular origin
Brief summary
It is generally estimated that 5 % of patients with thyroid cancer will develop distant metastases, and most of them had an advanced stage of the disease at presentation. Thirty per cent of them are resistant to radio iodine therapy and are called refractory. Their long term survival is estimated to be less than 10 %. The objective of this study is to identify the factors associated with poor outcome in a cohort of patients with advanced thyroid cancer followed during 5 years. Anaplastic and medullary thyroid carcinomas were excluded.
Interventions
OTHERfollow up visit
At least 1 follow up visit per year will be done and an additional visit if needed.
Sponsors
Hospices Civils de Lyon
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Man or woman ≥ 18 years. * Thyroid cancer differentiated from follicular origins (papillary, vesicular or poorly differentiated carcinoma). * TNM classification: stage pT3 (≥2 cm), or pT4 or M1 at diagnosis. * Patient after post operative radioiodine therapy.
Exclusion criteria
* Patient who can not be followed during the protocol. * Patient who does not consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of Thyroid cancer evolving to refractory stage | 5 years |
Countries
France
Outcome results
None listed