The Difference of Reflux Pattern Between the Patients Who Have Postprandial Reflux Symptoms

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02154659

Enrollment

Registered

2014-06-03

Start date

2014-06-30

Completion date

2015-12-07

Last updated

2019-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroesophageal Reflux Disease

Brief summary

Gastroesophageal reflux disease is increasing worldwide. The causes of reflux symptoms are not found exactly. especially, the postprandial reflux symptoms are more common than the all day reflux symptoms. One of the causes of reflux symptoms is the relaxation of the lower sphincter of the esophagus. But, the sphincter relaxation also occur in normal people. But, there is a difference in postprandial reflux pattens between the patients and the normal people. So, in this study, we want to compare the difference of reflux pattern between the patients who have postprandial reflux symptoms and normal people though the 24hr pH monitoring.

Interventions

DEVICE24hr pH monitoring

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

1. over 19 years old, male and female 2. normal people (control group, who has no postprandial reflux symptoms 3. patients who have postprandial reflux symptoms (postprandial reflux symptom means that within the last 6 months, postprandial reflux symptoms more than once a week for more than 1 month)

Exclusion criteria

1. patients who have nasoesophageal stricture 2. patients who have bleeding tendency 3. patients who have esophageal varix 4. patients who have cardioverter implantation 5. patients who had surgery for esophagus, stomach or duodenum 6. patients who are taking medications, gastrointestinal motility drugs

Design outcomes

Primary

Measure	Time frame	Description
The difference of reflux pattern at postprandial period between the patients who have postprandial reflux symptoms and the normal people	Within the 24 hours after the 24hr pH monitoring	Primary Outcome - The difference of reflux pattern at postprandial period between the patients who have postprandial reflux symptoms and the normal people The postprandial reflux symptom means that the symptoms more than once for a week for more than 1 month

Secondary

Measure	Time frame
The difference of esophageal reflux pH between the patients who have postprandial reflux symptoms and the normal people	Within the 24 hours after the 24hr pH monitoring

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026