Attention Deficit Hyperactivity Disorder, Healthy Controls
Conditions
Brief summary
The purpose of this research is to assess and determine brain oscillations or brain signatures of adult participants with Attention Deficit Hyperactivity Disorder (ADHD) relative to adult participants without ADHD using the technique electroencephalogram (EEG). Electroencephalogram is entirely non-invasive way of tracking brain activity.The main goal of this study is to establish biological factors for determining the diagnosis of Attention Deficit Hyperactivity Disorder (ADHD).
Interventions
The electroencephalogram assesses brain electrical activity through surface recording disks (electrodes) which are placed near the participants' head using a custom designed Lycra cap. The electrodes transmit the signals which are then amplified and stored on a computer. The procedure is entirely non-invasive. Once an accurate signal is assured, the signal derived from the electrode cap is then amplified, transmitted to a computer, and stored for later analysis. Each participant will undergo the electroencephalogram (EEG) procedure only once for the duration of 30-45 minutes.
Sponsors
University of Michigan
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
for all: * Right-handedness Inclusion Criteria for Attention Deficit Hyperactivity Disorder (ADHD) group: * Currently unmedicated adults with ADHD. To be given a full diagnosis of adult ADHD, the participant must have full Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-R) criteria: (1) described a chronic course of ADHD symptomatology from childhood to adulthood, and (2) endorsed a moderate or sever level of impairment attributed to the ADHD symptoms.
Exclusion criteria
for all: * Currently taking psychoative medications * Any clinically significant neurological problem (e.g., tics, seizures, serious head injury) * Alcohol or substance abuse (current or in the past 2 years) * Any current Axis I psychiatric diagnosis (other than ADHD) as verified by clinical interview
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Brain Wave Measurements | Two years | Measurement of electroencephalogram amplitude and coherence in alpha, gamma, and theta brain wave bands. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Default Network Signatures | two years | Measurement of the brain's default network consisting of interconnected midline and lateral parietal regions involved in internally directed mentation. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Comparison of dependent measurements between Attention Deficit Hyperactivity Disorder and healthy controls | two years | Comparison of dependent measures (i.e., computer tasks performed during electroencephalogram \[EEG\]: the Resting task and the Attention Control Task) between Attention Deficit Hyperactivity Disorder and healthy controls with independent sample t-tests. |
Countries
United States
Outcome results
None listed