Uncomplicated Neonatal Hyperbilirubinemia
Conditions
Keywords
Neonatal hyperbilirubinemia, Phototherapy, Light emitting diodes, Blue light, Turquoise light
Brief summary
The optimal wavelength for phototherapy for neonatal jaundice remains to be clarified by clinical studies. Previous iv vivo studies have shown that turquoise light at wavelength about 490 nm is more efficacious than blue light at wavelength 460 nm, which is the golden standard in phototherapy treatment today. Though, previous studies used light tubes, today we use light emitting diodes (LED'S). The overall aim of this study was therefore to compare the efficacy of turquoise LED's versus blue LED's for decreasing total serum bilirubin in neonates with gestational age \> 33 weeks and uncomplicated hyperbilirubinemia.
Interventions
OTHERPhototherapy
The infants were randomized to phototherapy with either blue og turquoise light
Sponsors
University of Aarhus
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
33 Weeks to No maximum
Healthy volunteers
No
Inclusion criteria
* Newborns with gestational age \>33 weeks and neonatal hyperbilirubinemia requiring treatment with phototherapy according to the national guidelines
Exclusion criteria
* Haemolytic disease (Rhesus and Kell blood type isoimmunization, spherocytosis) * Liver disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Decrease in total serum bilirubin | 24 hours | The infants were treated with phototherapy for 24 hours, which is the standard treatment. |
Countries
Denmark
Outcome results
None listed