Obesity;
Conditions
Keywords
anthropometric parameters;, biochemical parameters;, inflammatory markers, neuropeptide markers, phototherapy
Brief summary
Obesity is a chronic disease of increasing prevalence, being currently considered a global epidemic, including children, adolescents, adults and the elderly of different nationalities and ethnicities, socioeconomic levels, education levels. Non-pharmacological therapeutic interventions, such as physical exercise and fitness healthy eating strategies seem to be increasingly studied and recommended for healthy weight loss. In addition, therapies that can complement the effect of exercise and diet for reducing body weight are considerate important strategies. Thus, experimental evidence shows that the use of laser therapy combined with exercise swimming was effective in controlling the lipid profile, reducing the mass of adipose tissue, suggesting increased metabolic activity and changes in lipid metabolism. To investigate the effect of the use of therapeutic laser when associated to exercise like response to new therapy for weight loss and decrease of dyslipidemias levels.
Detailed description
Methods: During 20 weeks, each patients will receive 3 session of exercise with duration of 1 hour. Each session of exercise will composed of aerobic exercise and resistence exercise. After training session, each patient will receive application of phototherapy during 16 minutes. The protocol of phototherapy appplication is described in link interventions
Interventions
RADIATIONPhototherapy
phototherapy: all patientes will received application of phototherapy after exercise session. The phototherapy will be applicated in abdominal and dorsal circumference/ quadriceps and biceps femoral. Type Ga-Al-As Wavelength 808nm Frenquency Continue wave Optical output 100mW Spot diameter 0.6mm Power density 60W/cm2 Energy per minute 6J/point Number of Points 64points Total energy delivered 48J
Sponsors
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Fundação de Amparo à Pesquisa do Estado de São Paulo
Universidade Federal de Sao Carlos
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* volunteers aged 20-40 years with a body mass index (BMI) ≥ 30 above, of both genders with primary obesity;
Exclusion criteria
* The criteria for inclusion are volunteers who use contraceptive use, cortisone, anti-epileptic drugs, history of kidney and heart disease, alcohol abuse, smoking, use of supplemental vitamins or secondary diagnosis of obesity. After the pre-selection in the initial interview, the volunteers who contemplate all the inclusion criteria will be referred for clinical evaluation with an interdisciplinary health team and the electrocardiogram stress test to verify the release of the practice of physical exercises proposed by the project .
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Anthropometric measure | the measure occur up to 20 weeks | Weight body: this measure would occurs during each week. |
| anthropometric parameter | the measure occur up to 20 weeks | total body fat: this measure would occurs during each week |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Primary biochemical analyzes | the measures occur up to 20 weeks | The primary biochemical: glicemic variables (glucose and insulin) |
Other
| Measure | Time frame | Description |
|---|---|---|
| measure of neuropeptide | measures up to 20 weeks | neuropeptides variables: neuropeptide Y (NPY); agouti-related peptide (agRP); melanotropic hormone (MCH); Leptine; alpha melanocyte stimulating (alpha MSH); Pro-opiomelanocortin (POMC); Cocaine-Amphetamine-Regulated Transcript (CART); |
| measure of interleukines and citokines | the measure occur up to 20 weeks | interleukines and citokines variables: iL-1; iL-4; iL-6; iL-10; c reactive protein. |
Countries
Brazil
Outcome results
None listed