Malaria, Pneumonia
Conditions
Keywords
Impact of home management of malaria and pneumonia on child mortality, home management of malaria and pneumonia
Brief summary
A well-implemented community-based program of early and appropriate treatment of fevers/malaria episodes and pneumonia,will improve child survival as measured by a reduction of the less than five mortality rate.
Detailed description
An integrated approach of home and community management of malaria and pneumonia may increase the proportion of children receiving prompt treatment; improve child survival as measured by a reduction of the under five mortality rate. To test this hypothesis, a cluster randomised controlled trial will be performed, involving children less than 5 years of age, in Burkina Faso using a community-based supplying community health workers (CHWs), a core group of mothers (KOLs) with Coartem and cotrimoxazole specially packed in age-specific blisters containing a full course of treatment. The study will be carried out in 111 clusters of a rural district in Burkina Faso where malaria and pneumonia are two major mortality causes in under five mortality.
Interventions
OTHERhome/community case management
Sponsors
World Health Organization
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
6 Months to 59 Months
Healthy volunteers
No
Inclusion criteria
* living in one of the study cluster (villages) * no story of allergy to any of the study drugs * history of fever or body temperature \>= 38.5°C
Exclusion criteria
* signs of severity/complications like impaired consciousness, convulsions, fast breathing etc
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of death in children aged 6 to 59 months | 12 months | annual crude mortality rate in children aged 0 to 6 months in the different study arms |
Secondary
| Measure | Time frame |
|---|---|
| - specific mortality preceded by acute febrile illness of children aged 6 to 59 months - severe malaria cases at community level | 12 months |
Other
| Measure | Time frame |
|---|---|
| Adverse events at community level consecutive to the administration of the cotrimoxazole and arthemeter/lumefantrine | 7 days after the administration of the drug |
Countries
Burkina Faso
Outcome results
None listed