Non-surgical Periodontal Treatment on Hemogram, Lipid and Glycemic Profiles in Patients With Coronariopathies

Effects of Non-surgical Periodontal Treatment on Hemogram, Lipid and Glycemic Profiles of Patients With an Indication for Surgical Coronary Revascularization

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02150005

Enrollment

Registered

2014-05-29

Start date

2009-01-31

Completion date

Unknown

Last updated

2014-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronariopathy, Periodontitis

Keywords

periodontal diseases, cardiovascular diseases, periodontitis treatment

Brief summary

Objective: The aim of this study was to examine the effects of non-surgical periodontal treatment on the hemogram, glycemic and lipid profiles in cardiopathic patients with an indication for surgical revascularization. Materials and Methods: Twenty-two patients with chronic periodontitis, over 35 years of age (mean age 59.45 years) randomly assigned into 2 groups were evaluated. Test group (n=11), received periodontal treatment before the surgical procedure, and control group (n=11), did not received periodontal treatment prior to surgery.

Interventions

PROCEDUREPeriodontal treatment

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

35 Years to No maximum

Healthy volunteers

Inclusion criteria

* Undergoing cardiovascular treatment; * Eight viable teeth in the oral cavity; * Four periodontal sites with periodontal probing depths ≥5mm in different teeth.

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Low density lipid	Baseline and 90 days after initial exam	Non-significant reduction in test group. Mean difference of 8.9 mg/dL.
Reduction in probing depth in sites with PPD>3mm	Baseline and 90 days after the initial exam	Reduction of 11.4% in probing depth in sites with Periodontal Probing Depth\>3mm
Reduction in probing depth in sites with PPD>5mm	Baseline and 90 days after the initial exam	Reduction of 6.3% in probing depth in sites with Periodontal Probing Depth\>5mm
Reduction in probing depth in sites with CAL>3mm	Baseline and 90 days after the initial exam	Reduction of 4.6% in probing depth in sites with Clinical Attachment Level \>3mm.
Reduction in probing depth in sites with CAL >5mm	Baseline and 90 days after the initial exam	Reduction of 3.6% in probing depth in sites with Clinical Attachment Level \>5mm.
Leukocyte count	Baseline and 90 days after the initial exam	Non-significant reduction of leukocyte count in the test group. Mean difference of 74.6 m/mcL.
Glucose	Baseline and 90 days after the initial exam	Glucose showed a non-significant increase in the test group. Mean difference of 24.2 mg/dL.
Hemocyte	Baseline and 90 days after initial exam	Hemocyte presented a non-significant reduction in the test group. Mean difference 0.39 m/mcL
Hemoglobin	Baseline and 90 days after initial exam	Non-significant reduction in test group. Mean difference of 0.2 g/dL
Total Cholesterol	Baseline and 90 days after initial exam	Significant reduction in the test group. Mean reduction of 27.4 mg/dL.
High density lipid	Baseline and 90 days after initial exam	Significant reduction in test group. Mean difference of 8.2 mg/dL.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026