Optic Disc Swelling
Conditions
Keywords
idiopathic intracranial hypertension, optic disc swelling, antiacne medication, isotretinoin
Brief summary
The exact incidence of optic disc swelling and idiopathic intracranial hypertension in patients using antiacne medication is not known so far. The investigators hypothesize that swelling of retinal nerve fibre layer measured by optical coherence tomography is more frequent then assumed so far.
Detailed description
Measurement of retinal nerve fibre layer using optical coherence tomography over a period of 6 to 9 months depending on exact antiacne medication.
Interventions
OTHERRetinal nerve fibre layer measurement
Measurement of retinal nerve fibre layer thickness using optic coherence tomography.
Sponsors
University Hospital, Zürich
University of Zurich
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Antiacne medication treatment indicated by dermatologist * age \> 18 years * contraception if indicated
Exclusion criteria
\- age \< 18 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Retinal nerve fibre layer | 9 months | Measurement of retinal nerve fibre layer using optical coherence tomography. Changes over 10 micrometers are considered to be clinically relevant. The Term retinal nerve fibre layer describes an automated standardized optical coherence tomography measurement program measuring the sectorial thickness of the peripapillar retinal nerve fibre layer. There exists no other term for that. |
Countries
Switzerland
Contacts
Primary ContactGregor Jaggi, MD
Backup ContactIsabelle Meneau
Outcome results
None listed