Neonatal Hypocalcemia, Neonatal Sepsis
Conditions
Keywords
vitamin D, cord blood, neonatal sepsis, neonatal morbidity
Brief summary
Cholecalciferol (vitamin D3) is a prohormone and its active form is 1,25 dihydroxycholecalciferol. This hormone has effect on both calcium, phosphorus and bone metabolism and also bone morrow, muscle, heart and immune system. For a long time, maternal low vitamin D level is a well known problem for our country and the level was reported as \<10 ng/ml for 46-80% of mothers.The most prominent risk factor was determined as low socioeconomic status. Therefore, the level of 25-hydroxy-vitamin D is supposed to be in relation with several neonatal morbidities and maternal complications of pregnancy.
Interventions
None listed
Sponsors
Zekai Tahir Burak Women's Health Research and Education Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 30 Minutes
Healthy volunteers
No
Inclusion criteria
* Term or preterm newborns which are hospitalized in the Neonatal Intensive Care Unit of our hospital
Exclusion criteria
* Preterm babies born before the 24. gestational week * Babies with complex cardiac anomalies and/or dysmorphic features
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| maternal complications of pregnancy | from the beginning of gestation until birth process |
| sepsis | 3 months but patients will be followed until discharge |
| feeding intolerance | 3 months but patients will be followed until discharge |
| hypocalcemia | 3 months but patients will be followed until discharge |
| bronchopulmonary dysplasia | 3 months but patients will be followed until discharge |
| patent ductus arteriosis | 3 months but patients will be followed until discharge |
| retinopathy of prematurity | 3 months but patients will be followed until discharge |
Secondary
| Measure | Time frame |
|---|---|
| rachitism | 4 months but patients will be followed until discharge |
Outcome results
None listed