Foregut Subepithelial Lesions, Gastrointestinal Stromal Cell Tumors
Conditions
Keywords
GIST, endoscopy, endoscopic ultrasound
Brief summary
Specific Aim 1: To determine patient compliance with a GIST surveillance program Hypothesis: Patient compliance with a GIST surveillance program will be low. Specific Aim 2: To determine if EUS features of GIST, particularly maximum size, change significantly during a surveillance program. Hypothesis: EUS features of GIST, particularly maximum size, will not change significantly during a surveillance program. Specific Aim 3: To determine if EGD measures of GIST size correlate well with EUS measures of GIST size. Hypothesis: EGD measures of GIST size will correlate well with EUS measured of GIST size.
Interventions
None listed
Sponsors
Northwestern University
Washington University School of Medicine
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* presenting for EUS with an indication for a SEL in the stomach or esophagus * at least 18 years of age * able to provide informed consent
Exclusion criteria
* no subepithelial lesion in the stomach or esophagus' * less than 18 years of age * unable to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determine the natural history of small (< 30 mm) SELs discovered evaluated by EUS. | 3 years |
Secondary
| Measure | Time frame |
|---|---|
| Determine the degree of patient compliance with surveillance recommendations. | 3 years |
| Describe the diagnostic yield of EUS±FNA in evaluating SELs. | 2 weeks |
| Compare SEL size estimation based on EUS, EGD and computer tomography (CT). | 1 day |
Countries
United States
Outcome results
None listed