Postoperative Sleep Quality
Conditions
Keywords
postoperative, sleep quality, propofol, sevoflurane
Brief summary
The investigators designed a study to determine whether Propofol or Sevoflurane would provide same postoperative sleep quality in patients undergoing thyroidectomy.
Detailed description
The investigators designed a study to determine whether Propofol or Sevoflurane would provide same postoperative sleep quality in patients undergoing thyroidectomy.The bispectral index score (BIS) was monitored during the operation and the first postoperative night.
Interventions
DRUGpropofol
introvenious infusion of propofol
DRUGsevoflurane
sevoflurane (1.0-1.3 Minimum Alveolar Concentration)
Sponsors
China Medical University, China
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Participants were deemed eligible if they were candidates for general anesthesia undergoing thyroidectomy
Exclusion criteria
* Patients were excluded if they had a body mass index exceeding 30 kg/m2, had a Pittsburgh Sleep Quality Index global scores higher than 6, had an anesthesia time longer than 4 hours, had a history of cardiovascular, neurological, or psychiatric disease, had cervical lymph node metastasis, were treated with sedative and analgesics during the postoperative BIS-Vista monitoring period, were allergic to drugs used in the study, or had been diagnosed with Graves' disease or hyperthyroidism or hypothyroidism.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The Change of postoperative sleep quality | preoperation, first postoperative night | The primary outcome was the postoperative sleep quality, which was measured by the BIS-Vista monitor on the first night after surgery. |
Countries
China
Outcome results
None listed