Tic-Disorder
Conditions
Keywords
Tic-Disorder, Tourette-Disorder, Habit Reversal Training, Resources activation
Brief summary
The main purpose of this study is to evaluate the efficacy of a habit reversal based treatment programme compared to an alternative treatment which aims at the activation of resources in children and adolescents aged 8 to 18 years with tic disorders.
Detailed description
The main purpose of this study is to evaluate the efficacy of a habit reversal based treatment programme (THICS, Woitecki & Döpfner, 2014) compared to an intervention aimed at the activation of resources (STARK, Perri et al., 2014) for children and adolescents with tic disorders. This habit reversal treatment programme was developed at the Department of Child and Adolescent Psychiatry and Psychotherapy at the University of Cologne and has already been evaluated in a pilot-study (Woitecki & Döpfner, 2011, 2012). The activation of resources treatment programme was also developed at this Department and is currently evaluated in different studies. Effects are expected in both interventions, but a larger effect is expected in the THICS treatment
Interventions
BEHAVIORALHabit Reversal Training
awareness training, competing response training
BEHAVIORALResources activation
Sponsors
University of Cologne
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
8 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* 8-18 years * Diagnosis of chronic motor or vocal Tic (F95.1) or Tourette-Syndrome (F95.2) * YGTSS total score F95.2\>13, F95.1\>9 * Tics are the main problems * Intelligence IQ\>80 * If medication, then has been stable for at least one months in medicated patients * No change in medication treatment is planned * Ability to participate in weekly outpatient treatment * Acceptance of randomization
Exclusion criteria
Diagnosis of Autism Spectrum Disorder or Psychosis Parallel continuous psychotherapy of tics or comorbid -
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in Symptom Checklist for Tic-Symptoms (FBB-TIC, parent rating) at week 8, 16 and 24 | eight weeks (T1), sixteen weeks (T2) and 24 weeks (T3) | The FBB-TIC is used to assess Tic-Symptoms according to DSM-IV and ICD-10 rated by parents |
| Change in Quality of Life (Tic-HRQoL-FBB)(parent rating) | eight weeks (T1) and twenty-four weeks (T3) | The Tic-HRQoL-FBB is used to assess impairment and quality of life through tic symptoms and other comorbid symptoms rated by parents |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change of comorbid ADHD Symptoms (FBB/SBB-ADHD), parent, teacher and self-rating | eight weeks (T1), and 24 weeks (T3) | The Symptom Checklist for Attention Deficit/Hyperactivity Disorder (FBB-/SBB-ADHS) assess all symptom criteria according to DSM IV and ICD-10. |
| Change of comorbid OCD Symptoms (ZWIK-E), parent-rating | eight weeks (T1), and 24 weeks (T3) | The ZWIK assess OCD criteria. |
| Change of comorbid Symptoms (CBCL/TRF/YSR), parent-/teacher-/self-rating | eight weeks (T1), and 24 weeks (T3) | The CBCL, TRF and YSR assess a variation of different criteria. |
| Change in Symptom Checklist for Tic-Symptoms (FBB-/SBB-TIC), Teacher-/self-rating | eight weeks (T1), sixteen weeks (T2) and 24 weeks (T3) | The SBB-TIC is used to assess Tic-Symptoms according to DSM-IV and ICD-10 rated by parents |
| Change in Tic-Symptoms (YGTSS-TIC), overall score | eight weeks (T1), sixteen weeks (T2) and 24 weeks (T3) | The YGTSS is used to assess Tic-Symptoms in a semi structured interview with parents and patients |
| Change in Tic-Symptoms (observation) | 24 weeks (weekly assessment) | Tic symptoms are observed through video tapes and are rated through clinicians. |
| Change in self-esteem (Harter-Scale-SBB)(self rating) | eight weeks (T1), and 24 weeks (T3) | The Harter-Scale is used to assess self-esteem |
| Change in Symptom Checklist for Tic-Symptoms, clinical rating | eight weeks (T1), sixteen weeks (T2) and 24 weeks (T3) | The Checklist is used to assess Tic-Symptoms according to DSM-IV and ICD-10 rated by clinicians |
Countries
Germany
Outcome results
None listed