Common Bile Duct Stones
Conditions
Keywords
common bile duct stones, diverticulum
Brief summary
Recurrent common bile duct stone is one of the risk factors of recurrent cholangitis. However, the exact pathophysiology or mechanism of recurrent cholangitis has not been established. Periampullary diverticulum and narrow angle of common bile duct have been postulated as risk factors of recurrent common bile duct stone. The aim of this study was to evaluate the association between periampullary dierticulum, angle of common bile duct and recurrent common bile duct stone.
Detailed description
Recurrent common bile duct stone is one of the risk factors of recurrent cholangitis. However, the exact pathophysiology or mechanism of recurrent cholangitis has not been established. Periampullary diverticulum and narrow angle of common bile duct have been postulated as risk factors of recurrent common bile duct stone. The aim of this study was to evaluate the association between periampullary dierticulum, angle of common bile duct and recurrent common bile duct stone. This study is patient-control setting study. Firstly, from July 2007 through February 2014, all the patients who were performed ERCP will be enrolled. The inclusion criteria is the patients with common bile duct stone. The exclusion criteria is patients with biliary stenosis, PSC, retained GB stone, or who were lost to follow-up. The main outcome is the association between periampullary diverticulum, common bile duct angle, and recurrent CBD stone. This will be evaluated by univariate and multivariate analyses.
Interventions
OTHERThe existence of periampullary diverticulum
Periampullary diverticulum has been postulated as risk factor of recurrent CBD stone.
OTHERCBD angle
Narrow CBD angle has been postulated as risk factor for the development of recurrent CBD stone
Sponsors
Chuncheon Sacred Heart Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients who were performed ERCP due to CBD stone or calculous cholangitis
Exclusion criteria
* Patients with biliary stricture, PSC, retained GB stone, or who were lost to follow-up.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The association between existence of periampullary diverticulum and recurrent CBD stone | retrospective (up to 8 years) | The association between existence of periampullary diverticulum and recurrent CBD stone will be assessed by univariate analysis.(unit of analysis: odds ratio, statistical method: Fisher's exact test) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The association between common bile duct angle and existence of recurrent CBD stone | retrospective (up to 8 years) | The association between common bile duct angle and recurrent CBD stone will be assessed by univariate analysis (unit of analysis: angle, statistical method: student's t test) |
Other
| Measure | Time frame | Description |
|---|---|---|
| The risk factors for the development of recurrent CBD stone | retrospective (up to 8 years) | The risk factors for the development of recurrent CBD stone will be assessed by multivariate analysis, based on results of univariate analyses. (statistical method: logistic regression analysis) |
Countries
South Korea
Contacts
Primary ContactJai Hoon Yoon, M.D.,Ph.D.
Outcome results
None listed