Thrombin Generation and Gestational Outcome

Thrombin Generation and Gestational Outcome in Women With Recurrent Pregnancy Loss

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02139670

Enrollment

Registered

2014-05-15

Start date

2013-10-31

Completion date

2017-12-31

Last updated

2018-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thrombophilia

Brief summary

In total 120 pregnant women's with history of recurrent miscarriages, are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant. The investigators will measure the thrombin generation in plasma assessed by the calibrated automated thrombogram (CAT). The relation between pregnancy outcome and thrombin measurements will be determined

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age \> 18 * signed inform consent * first trimester * two early miscarriages(before week 10) or one later abortions (after week 10)

Exclusion criteria

* Chronic treatment with aspirin or other anticoagulants

Design outcomes

Primary

Measure	Time frame
pregnancy outcome	2 years

Countries

Israel

Outcome results