Community Acquired Pneumonia
Conditions
Keywords
Community acquired pneumonia, CAP, CAPNETZ, age ≥18, infiltrate on chest X-ray, cough or production of purulent sputum, pathologic lung auscultation, fever, adults
Brief summary
The main objective of this study is to investigate prevalence and risk factors for community-acquired pneumonia (CAP) and its interaction with comorbidities in an unselected group of adult patients receiving outpatient and inpatient care. In addition, information on HIV as a risk factor for CAP and on CAP in immunocompromised patients is collected.
Detailed description
The CAPNETZ study is a prospective, multicenter observational study investigating community-acquired pneumonia (CAP). Patients are recruited from outpatient and inpatient settings at hospitals and from primary care physicians (primarily specialists) and are followed for a period of six months. All CAP patients who meet the inclusion and exclusion criteria, consent to participate, and in whom the presence of a newly developed, community-acquired pneumonia can be verified are invited to participate. The baseline examination includes a detailed medical history, medication history, and a physical examination to record clinical and vital signs. In addition, the results of routine clinical imaging are documented, and biosamples (blood, urine, and respiratory specimens) are collected for clinical chemistry and microbiological analysis. Further in-person visits to document the course of the disease and treatment, including the collection of additional blood samples, take place 3 and 7 days after study enrollment. Twenty-eight days after enrollment, the patient's health status, treatment course, and complications are assessed by telephone. Finally, after 180 days, a telephone survey is conducted to determine the patient's whereabouts and survival status. Apart from the collection of biomaterials, no interventions are required or planned; physicians treat their patients as they normally would.
Interventions
None listed
Sponsors
Study design
Eligibility
Inclusion criteria
* age ≥ 18 * infiltrate on chest X-ray * further Inclusion criteria (at least one must apply): cough or purulent sputum or pathologic lung auscultation (crackles) or fever
Exclusion criteria
* Hospitalization lasting longer than 48 hours prior to the diagnosis of the current pneumonia * Newly diagnosed, active pulmonary tuberculosis within the last 2 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| diagnosis | 2 weeks | Assessment of diagnosis: Patients will be asked for example, about their diagnosis, comorbidities, specific risk factors and pneumonia symptoms. |
| therapy | 2 weeks | Assessment of therapy: Patients will be asked about their therapy due to pneumonia symptoms, previous therapy, medication History etc. |
| hospitalization | 2 weeks | Assessment of hospitalization: Patients will be asked about hospitalization, date, time and duration of hospitalization due to pneumonia symptoms. |
Countries
Germany
Contacts
University Hospital Giessen and Marburg
University Hospital Jena
University Hospital Schleswig-Holstein
Charité - Universitaetsmedizin Berlin
Medical School Hannover
Capnetz Stiftung