Critical Care, Weaning of Mechanical Ventilation, Trans-thoracic Echocardiography, Mitral Doppler, Diastolic Function
Conditions
Keywords
weaning, Cardiac, Echocardiography, Mechanical Ventilation
Brief summary
Comparing the hemodynamic and cardiac effects of two types of weaning trials of mechanical ventilation in ICU patients of two French ICU.
Detailed description
Prospective clinical study in ICU with ventilated patients eligible to weaning trials of mechanical ventilation (ZEEP and tubing-spontaneous ventilation) comparing hemodynamic and cardiac effects evaluated by trans-thoracic echocardiography.
Interventions
Sponsors
University Hospital, Clermont-Ferrand
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients ventilated requiring first weaning trial of mechanical ventilation * Stable respiratory and hemodynamic conditions * Consent of patients or family * Arterial line * Ventilated patients
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| left ventricular filling pressure | after 1 hour | Echo-cardiographic evaluation is realized at the end of the weaning trial (1 hour) or less if failed |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of other echocardiographic parameters of left ventricular filling pressures | after 1 hour | Comparison of other echocardiographic parameters of left ventricular filling pressures (E, Ea, deceleration time) at the end of weaning trial |
Countries
France
Outcome results
None listed