Neonatal Hydronephrosis, Obstructive Uropathy, Pelviureteric Junction Obstruction, Pyeloplasty, Urinary Stent
Conditions
Keywords
Pelviureteric junction obstruction, pyeloplasty, Neonate affected by hydronephrosis, obstructive uropathy, urinary stent
Brief summary
to compare outcome of pyeloplasty in pediatric population less than 6 months in age using an after coming stent versus stentless pyeloplasty.
Detailed description
A prospective randomized control study including patients divided into two groups,all patient undergoes dismembered pyeloplasty First group will be with an after coming stent ,Second group will be stentless to compare outcome of pyeloplasty in pediatric population less than 6 months in age
Interventions
PROCEDUREAfter coming stent after dismembered pyeloplasty
Dismembered pyeloplasty through lumbar incision. The patients who are randomized to the after coming stent arm, an after coming stent is inserted. Distal part of it is positioned in the mid ureter. The proximal end is passed through the renal parenchyma (usually the lower kidney calyx) to be exteriorized through stab wound and fixed to the skin. The size of external stent is 4-5 F.
PROCEDUREStentless dismembered pyeloplasty
Dismembered pyeloplasty through lumbar incision. No stents are inserted
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 6 Months
Healthy volunteers
No
Inclusion criteria
* Pelvi-ureteric junction obstruction (PUJO) * Asymptomatic obstruction with reduced function (less than 35-40%) * Asymptomatic obstruction with antero-posterior diameter exceed 40 mm * Asymptomatic obstruction with deterioration on conservative follow up. * Symptomatic PUJ obstruction, e.g. pain, renal mass, fever and stones.
Exclusion criteria
* Secondary Pelvi-ureteric junction obstruction * Solitary kidney * Gross pyuria * Ectopic kidney * Dilated ureter
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 2ry intervention | 1 month | Need for 2ry intervention in the form of insertion of ureteral stent |
| Fever | 1 month | Postoperative fever |
| Postoperative Hospital stay | 1 week | Postoperative Hospital stay |
| Leakage | 1 week | occurrence of post operative leakage |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of kidney function after repair | 6 months | \- Assessment of kidney function after repair using renogram and ultrasound |
| success | 6 months | Need for 2ry treatment of persistent pelviureteric junction obstruction |
Countries
Egypt
Outcome results
None listed