Atrial Fibrillation
Conditions
Keywords
atrial fibrillation, catheter ablation, recurrence
Brief summary
1\. Purpose of the study 1\) To explore clinical recurrence associated clinical factors including age, sex, clinical, electrophysiological, anatomical, imaging, and serologic characteristics. 2\) To develop simulation model to predict clinical recurrence and the efficacy of catheter ablation 2. Scientific evidence of the study 1. In atrial fibrillation patients, the maintenance of normal sinus rhythm showed significant reduction of mortality. 2. drug therapy with anti-arrhythmic drug showed many complications and side effect, thus non-drug therapy such as catheter ablation is developed. 3. catheter ablation has been performed for 10years world-wide, and showed superior treatment outcome compared with drug therapy. 4. clinical outcome after catheter ablation is affected not only by age, sex and underlying disease, but also by electrophysiologic, imaging, serologic and electroanatomical remodeling of the heart. However, there are few studies concerning these multifactorial variables. 3\. Study population
Interventions
None listed
Sponsors
Yonsei University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients who undergoing catheter ablation of atrial fibrillation due to symptomatic, drug refractory atrial fibrillation
Exclusion criteria
* patients who do not agree with study inclusion * permanent AF refractory to electrical cardioversion * AF with valvular disease ≥ grade 2 * patients with left atrial diameter greater than 60mm * patients with age less than 19
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical recurrence of atrial fibrillation (AF) after catheter ablation | Participants will be followed for 5 year after catheter ablation | We defined recurrence of AF as any episode of AF or atrial tachycardia lasting longer than 30 sec. Patients were asked to attend scheduled outpatient follow-up appointments 2, 6, 12, 18, 24, 36, 48 and 60 months after catheter ablation. |
Countries
South Korea
Contacts
Primary ContactHui-Nam Pak, MD
Outcome results
None listed