Neurogenic Lower Urinary Tract Dysfunction, Spinal Cord Injury
Conditions
Keywords
diffusion tensor imaging fiber tracking, magnetic resonance Imaging, spinal cord injury, neurogenic lower urinary tract dysfunction
Brief summary
The exact innervation of the bladder and the changes after a spinal cord injury have been not yet been illustrated. Diffusion tensor imaging with magnetic resonance imaging is a new technique which can be used to visualize single nerve fibers, and thus represent the neural supply of a region in vivo. There are studies in which both the sacral plexus and the lumbar nerve roots have been represented using diffusion tensor imaging. However, there is no study concerning the innervation of the bladder. The investigators are therefore using diffusion tensor imaging with magnetic resonance imaging to represent the bladder innervation of individuals with neurogenic lower urinary tract dysfunction and individuals with normal bladder function.
Interventions
None listed
Sponsors
Swiss Paraplegic Research, Nottwil
Study design
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* neurogenic lower urinary trat dysfunction * normal bladder function
Exclusion criteria
* no signed informed consent * contraindications for MRI (pace maker, implanted metal, claustrophobia) * upper or lower urinary tract surgeries * pregnancy (anamnestic)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| bladder innervation quality | day 0 | bladder innervation is illustrated using diffusion tensor imaging fiber tracking with magnetic resonance imaging |
Countries
Switzerland
Outcome results
None listed