The Effect of Spinal Anesthesia on Heart Rate Variability in Diabetic Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02137057

Enrollment

Registered

2014-05-13

Start date

2014-05-31

Completion date

2014-12-31

Last updated

2015-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes, Heart Rate Variability, Spinal Anesthesia

Keywords

Heart Rate Variability, spinal anesthesia, DM, cardiac autonomic dysfunction

Brief summary

Cardiac autonomic neuropathy is a common complication of diabetes and is associated with resting tachycardia. Regional anesthesia could interrupt normal autonomic activity by central sympathetic blockade. The investigators evaluate the relation of severity of diabetes and heart rate variability, also the impact of spinal anesthesia on the change of heart rate variability.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

40 Years to 80 Years

Healthy volunteers

Inclusion criteria

* patients undergoing lower limb surgery with spinal anesthesia (ASA class 1,2,3)

Exclusion criteria

* severe coagulopathy, short height, arrhythmia patients, patients taken medication which could affect autonomic nervus system (bata- blocker or alpha-blocker)

Design outcomes

Primary

Measure	Time frame
Change of Heart rate variability during spinal anesthesia : total power, power of LF and HF, and LF/HF ratio	10 min before spinal anesthesia (T0: Baseline ) 10 min (T1), 20 min (T2) and 30 min (T3) after spinal injection

Countries

South Korea

Outcome results