Staining Effect of Chlorhexidine
Conditions
Brief summary
The aim of this clinical trial was to evaluate through a clinical spectrophotometric analysis the staining side effect of a 0.2% CHX mouthwash containing an anti discoloration system (ADS) compared with a 0.12% and a 0.2% CHX alone mouthwash after periodontal surgery. The efficacy of the products and the patient's opinion and acceptance were also assessed.
Interventions
DRUGChlorhexidine
Sponsors
dott. Lorenzo Bevilacqua
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Good general health conditions without a medical history of medication that might interfere with periodontal tissues * Good plaque control (FMPS ≤ 25%) and low levels of infection (FMBS ≤ 25%) * Need for periodontal surgery
Exclusion criteria
* Smokers * Allergy to CHX * Lack of written informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in ΔE before and after the use of chlorhexidine | Change from Baseline of ΔE after the use of chlorhexidine mouthrinses; change from Baseline of ΔE after the use of chlorhexidine mouthrinses at 1 week; change from Baseline of ΔE after the use of chlorhexidine mouthrinses at 2 weeks | Change in ΔE before and after the use of chlorhexidine (ΔE is a measurement used to indicate how much a color deviates from an accepted standard. Perfect color has a ΔE of zero.) |
Countries
Italy
Outcome results
None listed