Healthy
Conditions
Keywords
iron absorption, healthy females, child bearing age
Brief summary
The purpose of this study is to study the effect of a probiotic product on iron absorption in healthy females of child-bearing age.
Interventions
DIETARY_SUPPLEMENTL plantarum DSM 9843 or placebo
Sponsors
Probi AB
Study design
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Eligibility
Sex/Gender
FEMALE
Age
19 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Female * Age ≥19 and ≤45 years * Hb \>117g/L
Exclusion criteria
* Gastrointestinal diseases * Metabolic diseases * Use of other probiotic products during the study and 2 weeks before the study start * Pregnant or breast-feeding * A serum ferritin level \>60 µg/L * Medication (oral contraceptives allowed) * Intake of dietary supplements (incl. iron) during the study and two weeks before the study start * No blood donation in the last 2 months * High C-reactive protein levels
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Iron absorption ratio in blood samples | 14 days | Iron absorption will be estimated by measuring the isotope ratio (55Fe/59Fe) in blood after addition of iron isotopes in test meals (55Fe in placebo meal, 59Fe in L plantarum DSM 9843 meal). |
Countries
Sweden
Outcome results
None listed