Telomeres Parameters in Cirrhosis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02131831

Enrollment

Registered

2014-05-06

Start date

2014-06-30

Completion date

2015-12-31

Last updated

2014-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cirrhosis

Keywords

telomere, telomerase, cirrhosis

Brief summary

There are several factors that influence telomere length in patients with cirrhosis, such as metabolic derangements and infectious etiologies, The aim of the study is to compare telomere length and other parameters related to genetic instability in telomere/ telomerase system, in peripheral blood lymphocytes in cirrhosis from different etiologies.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* cirrhotic patients from different etiologies

Exclusion criteria

* decompensated cirrhosis (Child C) * age under 18 years * any known malignancy, including hepatocellular carcinoma * patient that are unable to sign for informed consent

Design outcomes

Primary

Measure	Time frame	Description
telomerase activity	baseline	number of copies of telomerase in peripheral blood lymphocytes, as determined by FISH

Countries

Israel

Contacts

Primary ContactIdo Laish, MD

ido.laish@gmail.com

Outcome results