Acute Cholecystitis: Early Versus Delayed Laparoscopic Cholecystectomy; Randomized Prospective Study

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02130245

Enrollment

600

Registered

2014-05-05

Start date

2013-09-30

Completion date

2016-01-31

Last updated

2015-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Cholecystitis

Keywords

Laparoscopic cholecystectomy, Acute cholecystitis, Early, Delayed

Brief summary

The best management of the acute cholecystitis is to do laparoscopic cholecystectomy. The hypothesis is that to do it as an early intervention after patient admission is better than delayed cholecystectomy regarding the hospital stay, interval for antibiotic, the easiness of the operative maneuver reflected by operative time, conversion and intraoperative complications.

Detailed description

Doing laparoscopic cholecystectomy for patients with acute cholecystitis as an early intervention after patient admission ( first group) or to do it after a while of treatment and conservation as a delayed cholecystectomy (second group) points of study include the hospital stay, interval for antibiotic, the easiness of the operative maneuver reflected by operative time, conversion and intraoperative complications.

Interventions

PROCEDUREEarly cholecystectomy

Early laparoscopic cholecystectomy for acute cholecystitis after admission

PROCEDUREDelayed cholecystectomy

Laparoscopic cholecystectomy well be done after a period on conservation

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Proved acute cholecystitis clinical, radiologic

Exclusion criteria

* Evidence of peritonitis * ASA III or IV * Previous upper abdominal surgery * Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Operative time	1 DAY	Operative time is assessed in minutes ,

Secondary

Measure	Time frame	Description
Perioperative complications	5 weeks	Intraoperative complications like bleeding , injury,
Conversion rate	1 DAY	Conversion rate from laparoscopic to open and reason of conversion.
hospital stay in days	2 weeks	hospital stay in days
Period of giving antibiotics in days	2 WEEKS	Number of days giving the antibiotics

Countries

Egypt

Contacts

Primary Contactmohamed e abdellatif, md

surg_latif@hotmail.com00201115051680

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026