Infertility
Conditions
Keywords
Infertility, IVF/ICSI, Progesterone, Preimplantation Factor (PIF)
Brief summary
The aim of this study is to achieve a more profound understanding of the endocrine alteration in luteal progesterone level after gonadotrophin stimulated IVF/ICSI cycles and to explore the optimal progesterone level needed for securing implantation and development of early pregnancy. The second part of the project will determine the value of Preimplantation Factor (PIF) measurement in embryo culture medium as a possible tool for improved embryo selection and the use of PIF as an early pregnancy serum marker for healthy implantation and embryo development. IVF: In vitro fertilisation, ICSI: Intracytoplasmic sperm injection.
Interventions
OTHERIVF/ICSI treatment
Sponsors
Ferring Pharmaceuticals
BioIncept LLC
Regionshospitalet Viborg, Skive
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
-All women undergoing IVF/ICSI treatment at the participating clinics in either antagonist protocol or long agonist protocol will be offered participation.
Exclusion criteria
-Prior participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| On-going pregnancy rate | 10th week of gestation |
Secondary
| Measure | Time frame |
|---|---|
| Implantation rate | 7th week of gestation |
Countries
Denmark
Outcome results
None listed