Iron Deficiency Anemias
Conditions
Keywords
Anemias, Iron-Deficiency, thrombin
Brief summary
In total 50 subjects with iron deficiency anemia treated with intravenous iron are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant before iron treatment. The investigators will measure the thrombin generation in plasma assessed by the calibrated automated thrombogram (CAT). patient will go face to face interview and will be asked to answer structured questionnaire which will include information on demographics, clinical data ( fever, allergies , etc.) and comorbidities Two weeks after completing intravenous iron administration additional blood samples will be taken: thrombin generation will be measured
Interventions
None listed
Sponsors
HaEmek Medical Center, Israel
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age \>18 years * Iron deficiency anemia that did not response to oral iron treatment and is planned to receive iron supplement intravenously. * Signing the informed consent
Exclusion criteria
* chronic inflammatory disease * renal failure * Malignancy * Infectious disease * Other reason for anemia except iron deficiency anemia. * Pregnant women * Use of anti aggregating agents or anticoagulants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| thrombin generation levels | 10 weeks |
Countries
Israel
Outcome results
None listed