Assessment of Ovarian Reserve Tests in Unexplained Infertile Women

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02127944

Enrollment

Registered

2014-05-01

Start date

2014-04-30

Completion date

2015-07-31

Last updated

2018-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility, Infertility, Female

Brief summary

IN UNEXPLAINED INFERTILITY IN WOMEN ,OVARY RESERVE IS BORDERLINE IF ASSESSED USING HIGH-SENSITIVE TESTS.

Detailed description

IN UNEXPLAINED INFERTILITY OVARIAN RESERVE TESTS WERE ASSESSED. IN THIS STUDY, A COMPARISON IS DONE BETWEEN 35 WOMEN WITH UNEXPLAINED FERTILITY(THE PATIENT) AND 35 WOMEN WHO DON'T HAVE ANY FERTILITY PROBLEMS AND HAVE AT LEAST A CHILD (THE CONTROL GROUP). THE STUDY PARTICIPANTS SHOULD HAVE THE FOLLOWING CRITERIA Inclusion Criteria: LESS THAN 35 YEARS OLD, MARRIED WOMEN SHOULD HAVE REGULAR MENSES SHOULD HAVE AT LEAST A YEAR OF UNPROTECTED SEX. THE HUSBAND'S SPERMOGRAM SHOULD HAVE NO ABNORMALITIES THE SUBJECT SHOULD HAVE A NORMAL HYSTEROSALPHINGOGRAPHY Exclusion Criteria: HAVING ANY SYSTEMIC DISEASE. LONG HISTORY OF ANY DRUG USAGE. FOR THE CONTROL GROUP Inclusion Criteria: LESS THAN 35 YEARS OLD, MARRIED WOMEN SHOULD HAVE REGULAR MENSES AT LEAST HAVE A CHILD THE HUSBAND'S SPERMOGRAM SHOULD HAVE NO ABNORMALITIES THE SUBJECT SHOULD HAVE A NORMAL HYSTEROSALPHINGOGRAPHY Exclusion Criteria: HAVING ANY SYSTEMIC DISEASE. LONG HISTORY OF ANY DRUG USAGE. THE STUDY INCLUDES THE FOLLOWING TESTS BEING DONE ON THE PATIENTS: THE FOLLOWING HORMONES' LEVELS WERE STUDIED:AMH (ANTI-MULLERIAN HORMONE),FSH (FOLLICULAR STIMULATING HORMONE) , E2 (ESTRADIOL) AND INHIBIN B.THE FORMER THREE HORMONE LEVELS SHOULD BE ASSESSED ON THE THIRD DAY OF MENSES IN THE STUDY,TRANSVAGINAL ULTRASONOGRAPHIC OVARIAN VOLUME ,OVARIAN ANTRAL FOLLICULE NUMBER,OVARIAN STROMAL BLOODFLOW AND OVARIAN ARTERIAL RESISTANCE WAS MEASURED USING DOPPLER ULTRASONOGRAM.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

21 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* LESS THAN 35 YEARS OLD, * MARRIED WOMEN * SHOULD HAVE REGULAR MENSES * SHOULD HAVE AT LEAST A YEAR OF UNPROTECTED SEX.

Exclusion criteria

* HAVING ANY SYSTEMIC DISEASE. * LONG HISTORY OF ANY DRUG USAGE.

Design outcomes

Primary

Measure	Time frame	Description
LEVELS OF OVARIAN RESERVE MARKERS IN THE SERUM	ONE DAY	AMH (ANTI-MULLERIAN HORMONE),FSH (FOLLICLE STIMULATING HORMONE),E2 (ESTRADIOL)AND INHIBIN -B LEVELS WILL BE TESTED

Secondary

Measure	Time frame	Description
ULTRASONOGRAPHIC ASSESSMENT OF OVARIAN RESERVE MARKERS	ONE DAY	OVARIAN ANTRAL FOLLICULE COUNT ,OVARIAN VOLUME MEASUREMENT,OVARIAN DOPPLER -ULTRASONOGRAPHIC ASSESSMENT

Countries

Turkey (Türkiye)

Outcome results