Influence of Synacthen Infusion on the Results of Adrenal Venous Sampling in Patient With Primary Aldosteronism

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02127840

Acronym

ISIRA

Enrollment

Registered

2014-05-01

Start date

2011-03-31

Completion date

2014-12-31

Last updated

2014-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Aldosteronism

Keywords

primary aldosteronism, adrenal adenoma, arterial hypertension

Brief summary

The project is aimed to determine the value of synacthen infusion on the results of adrenal venous sampling in patients examined for primary aldosteronism

Detailed description

We aim to compare the results of adrenal venous sampling performed without and during synacthen infusion.

Interventions

DRUGSynacthen infusion during adrenal venous sampling

Adrenal venous sampling during Synacthen infusion

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Confirmed primary aldosteronism

Exclusion criteria

Inability to undergo unilateral adrenalectomy

Design outcomes

Primary

Measure	Time frame
To verify whether Synacthen infusion may influence the results of adrenal venous sampling in patients with primary aldosteronism	End of clinical examination procedure, i.e. within 4 week after adrenal venous sampling is performed.

Countries

Czechia

Contacts

Primary ContactMiroslav Solar, MD

miroslav.solar@fnhk.cz+420495834739

Backup ContactJiri Ceral, MD

ceral.jiri@fnhk.cz+420495833249

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026