Celiac Disease
Conditions
Keywords
celiac, telomere, telomerase
Brief summary
Celiac disease is an autoimmune process that causes destructive changes in the epithel of the small bowel and it is also a pre-malignant state (e.g lymphoma). The aim of the study is to examine telomere length and other parameters of genetic instability from peripheral blood lymphocytes of patients with celiac disease compared with healthy controls.
Interventions
PROCEDUREtake blood samples
Sponsors
Meir Medical Center
Study design
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* patients with celiac disease
Exclusion criteria
* known malignancy * cannot sign informed consent * under age 18
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| telomere length | at entry, after 6 months of gluten-free diet |
Outcome results
None listed