Healthy Volunteers
Conditions
Brief summary
Transcranial direct current stimulation is a tool to modulate cortical excitability.
Detailed description
Anodal transcranial direct currenti stimulation over visual cortex is able to decrease the thermo-nociceptive sensibility and thermonociceptive potentials, whilst cathodal transcranial direct current stimulation has the opposite effect, it decreases VEP amplitude and habituation. This neuromodulation technique is probably a tool in the prevention in episodic and chronic migraine. The aim of the study is to study short and long term effect of tDCS over pain treshold, contact heat evoked potentials, blink reflex and visual evoked potentials in healthy volunteers.
Interventions
DEVICECefaly tDCS
Cefaly tDCS (transcranial direct current stimulation) is able to modify cortical excitability, in particular anodal tDCS increases it. The side effects of tDCS are minor, especially sensations of itching and scalp paresthesias.
Sponsors
University of Liege
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy volunteers
Exclusion criteria
* age below 18 or above 65 years * personal history of recurrent headache or other neurological diseases especially seizures, * familial history of recurrent headache * child migraine equivalents (motion sickness, cyclic vomiting or recurrent abdominal pain, somnambulism etc.. . .) * chronic pain syndromes * analgesics intake at the time of recording * contra-indications to tDCS neurostimulation (metal prosthetics in the head or internal stimulation like a pacemaker).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Neurophysiological mesures changes | up to 1 month | Modifications in neurophysiological test after direct current stimulation |
Other
| Measure | Time frame | Description |
|---|---|---|
| VEP changes | up to 1 month | Evaluation of changes in latency, amplitude, slope and habituation |
| Blink changes | up to 1 month | Evaluation of changes in latency, amplitude, slope and habituation |
| CHEPS changes | up to 1 month | Evaluation of changes in latency, amplitude, slope and habituation |
| Quantitave Sensory Testing | up to 1 month | Evaluation of changes in thresholds |
Countries
Belgium
Outcome results
None listed