Obese, Pregnancy
Conditions
Keywords
pregnancy, obese
Brief summary
The purpose of the study is to determine how a mother's health and physical activity may influence her child's growth and development.
Interventions
OTHERExercise Intervention
Sponsors
Arkansas Children's Hospital Research Institute
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* BMI \>30 * \>18 years of age * Singleton pregnancy * Less than 12 weeks gestation * Sedentary * Conceived without assisted fertility treatments * Cleared by physician to exercise
Exclusion criteria
* Women with pre-existing medical conditions as determined by the PI to affect the outcomes of interest * Women who are using recreational drugs, tobacco, or alcohol during pregnancy * Women with contraindications to exercise during pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Risk of obesity in infants and children | 2 years | Birth weight, body fat, and metabolism will be evaluated during the first 2 years of life. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Maternal insulin sensitivity | 9 months | Fasted blood samples will be analyzed to assess glucose and insulin. |
| Maternal inflammation | 9 months | Markers of inflammation will be investigated in fasted serum samples. |
Countries
United States
Outcome results
None listed