Heart Failure
Conditions
Keywords
Heart failure, Exercise tolerance, Noninvasive ventilation
Brief summary
The purpose of this study is to evaluate the effects of airway bilevel positive pressure on the improvement of exercise tolerance in patients with decompensated heart failure.
Detailed description
Heart failure causes limitation of functional capacity and worsening of exercise tolerance. The airway pressure as adjuvant of cardiac rehabilitation has demonstrated improvement of functional capacity, decrease of respiratory work, increase of oxygenation and pulmonary compliance. Objective: to evaluate the effectiveness of the bilevel positive airway pressure (BILEVEL) in the increase of exercise tolerance in patients with decompensated heart failure. Method: this is a cross-over randomized clinical trial, with individuals who will undergo a submaximal progressive exercise test of the lower limbs with a cycle-ergometer using continuous positive airway pressure (CPAP) and BILEVEL in a random order. Patients will also be evaluated using a health related quality of life questionnaire, pulmonary function test, inspiratory muscle and peripheral muscle strength tests. Hypothesis: The increase in exercise tolerance might be greater during the use of BILEVEL.
Interventions
DEVICEBiLevel
The intervention will be performed using BiLevel ventilation mode with EPAP=10 cmH2O and a IPAP which manages 6-8ml/kg tidal volume.
Sponsors
Hospital Sirio-Libanes
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* subjects who has heart failure functional class II or III of New York heart association * over 18 years * non-smokers * without cognitive or motor deficit * without vasoactive drugs or low doses * without recent acute myocardial myocardium (\<1 year) * without recent cardiac surgery (\<1 year) * without pulmonary disease * without bronchodilators
Exclusion criteria
* unstable angina * atrial fibrillation and atrioventricular block third degree * frequent vomiting * respiratory instability while collecting data
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endurance time of exercise in cycle ergometer. | 4 days |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Dyspnea | 4 days | Dyspnea will be evaluated by means of the modified Borg scale before and after exercise. |
Countries
Brazil
Outcome results
None listed